For example, the skin plays a key role in protecting the body against pathogens Its other functions are insulation, temperature regulation, sensation, and the production of vitamin D folates.
For example, hyaluronan, versican and decorin are present throughout the dermis and epidermis extracellular matrix, whereas biglycan and perlecan are only found in the epidermis.
It harbors many mechanoreceptors (nerve endings) that provide the sense of touch and heat through nociceptors and thermoreceptors.
All mammals have some hair on their skin, even marine mammals like whales, dolphins, and porpoises which appear to be hairless.
The skin interfaces with the environment and is the first line of defense from external factors.
It also contains the hair follicles, sweat glands, sebaceous glands, apocrine glands, lymphatic vessels and blood vessels.